6163银河网站入口官方网站欢迎您的光临!
免费咨询热线: 4008-750-250
科研细胞
药靶细胞
标准品
NGS靶向捕获探针
AI-Edigene® POLE p.P286R Reference Standard Plus
CBP10685
|
|
Format | Genomic DNA |
Description | POLE, DNA polymerase epsilon catalytic subunit, mediates proofreading activity during DNA repair and replication and plays a role in genomic stability. Somatic mutations in POLE have been identified in colorectal cancer, frequently in endometrial cancer, and are often associated with high tumor mutational burden, but are less likely to be associated with DNA mismatch repair (MMR) deficiency. |
Technical Data | |
DNA Change | c.857C>G |
AA Change | p.P286R |
Mutation type | Substitution - Missense |
Zygosity | Heterozygous |
Allelic Frequency | 50% |
Transcript | NM_006231.4 |
Cosmic ID | COSM937332 |
Chr position(GRCh38) | chr12-132676598-G-C |
Buffer | Tris-EDTA |
Product Information | |
Intended Use | Research Use Only |
Unit Size | 1ug |
Concentration | Download for COA |
Purofication | Download for COA |
DNA electrophoresis | Download for COA |
Sanger sequencing | |
Storage | 4℃ |
Expiry | 36 months from the date of manufacture |
扫一扫,关注我们公众号
Copyright ©2021 www.cobioer.com All Rights Reserved. 6163银河网站入口版权所有 苏ICP备13038923号